The Colors of Mice: A Model Genetic NetworkJohn Wiley & Sons, 5. 3. 2010 - Počet stran: 312 Serving the needs of pigment cell biologists, cellular physiologists, developmental geneticists, researchers interested in melanoma and more, this new book showcases a blend of new technologies and new insights in the field of pigmantary genetics of mice, with comparative information on other animals. Graduate students can learn here the terminology and scope of the field, and animal fanciers can discover the genetics behind common color variants of mammals. The book is hailed for being written by four of the premier scientists in the field. These authors aim to present the molecular /cellular work in the context of phenotype and the interacting functions of genes that direct the development and function of one biological system. For other researchers, the depth of genetic knowledge on the pigmantary system makes it a valuable model for the study of other systems. |
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The Colors of Mice: A Model Genetic Network M. Lynn Lamoreux,Véronique Delmas,Lionel Larue,Dorothy Bennett Náhled není k dispozici. - 2010 |
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abnormal activity Agouti locus albinism allele animals background belly spot brown chimeric chromosome coat color complex crest cells defects Developmental differentiation dogs EDN3 EDNRB embryo encoded enzymes epidermis eumelanic eumelanin eumelanin/pheomelanin expression Figure function gene genetic genome Genomic Sciences Center genotype graying hair follicle Hermansky–Pudlak heterozygous homolog homozygous human inbred interactions keratinocytes kinase KITL Lamoreux M.L. lethal ligand loci mammalian mammals MC1R melanin melanoblasts melanocortin melanocytes melanogenesis melanoma melanosome membrane mice mice mutant microphthalmia migration migratory MITF MMRRC molecular mouse murine mutant neural crest neural tube neural-crest cells nonagouti normal ofmice ofpigment ofthe organelles pattern PAX3 phenotype phenotypic alleles pheomelanic pheomelanin pigment cells pigment-cell lineage processes protein receptor recombination regulation result RIKEN Genomic Sciences signaling pathway Silver skin specific syndrome Targeted tissues tortoiseshell transcription factor transgenic transgenic mice transport tyrosinase TYRP1 vitiligo white spotting WNT signaling yellow