Dopamine Receptor Subtypes: From Basic Science to Clinical Application

Přední strana obálky
Peter Jenner, R. Demirdamar
IOS Press, 1998 - Počet stran: 163
Multiple subtypes of dopamine receptors exist in the brain. This volume reviews the characteristics of D-1, D-2, D-3 and D-4 receptors and describes the current concepts of their involvement in motor disorders and in the control of schizophrenia. Readers: the book will be of great interest to professionals in pharmacology, medicinal chemistry, neuroscience, cell biology and therapeutic applications in clinical medicine as antipsychotics, anti-Parkinson's disease and related areas.
 

Obsah

Preface
1
Biochemical Evidence for D Receptors not Linked to Adenylyl Cyclase
8
Alterations in Dopamine Neurotransmission Produced by Genetic Knockouts
29
Regulation of Psychomotor Behaviour
45
Dihydrexidine and Parkinsons
64
Efficacy of Dopamine D Receptor Agonists A86929 and ABT431 in Animal
84
The Physiological Role of Dopamine D2 Receptors Y Bozzi and E Borrelli
105
From Cloning to Function P Sokoloff N Griffon
130
Dopamine D and D Receptors as Potential Therapeutic Targets K A Svensson
148
Author Index
163
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